Frequency of positive polyanion antibody tests after COVID-19 vaccination

Quantitative analysis of COVID-19 pneumonia severity by CT pneumonia evaluation algorithm utilizing deep studying know-how and blood take a look at outcomes
Objective: To judge whether or not early chest computed tomography (CT) lesions quantified by a man-made intelligence (AI)-based business software program and blood take a look at values on the preliminary presentation can differentiate the severity of COVID-19 pneumonia.
Supplies and strategies: This retrospective research included 100 SARS-CoV-2-positive sufferers with delicate (n = 23), reasonable (n = 37) or extreme (n = 40) pneumonia categorized in response to the Japanese tips.
Univariate Kruskal-Wallis and multivariate ordinal logistic analyses have been used to look at whether or not CT parameters (opacity rating, quantity of opacity, % opacity, quantity of excessive opacity, % excessive opacity and imply HU whole on CT) in addition to blood take a look at parameters [procalcitonin, estimated glomerular filtration rate (eGFR), C-reactive protein, % lymphocyte, ferritin, aspartate aminotransferase, lactate dehydrogenase, alanine aminotransferase, creatine kinase, hemoglobin A1c, prothrombin time, activated partial prothrombin time (APTT), white blood cell count and creatinine] differed by illness severity.
Outcomes: All CT parameters and all blood take a look at parameters besides procalcitonin and APPT have been considerably totally different amongst delicate, reasonable and extreme teams. By multivariate evaluation, imply HU whole and eGFR have been two impartial elements related to severity (p < 0.0001). Cutoff values for imply HU whole and eGFR have been, respectively, – 801 HU and 77 ml/min/1.73 m2 between delicate and reasonable pneumonia and – 704 HU and 53 ml/min/1.73 m2 between reasonable and extreme pneumonia.
Conclusion: The imply HU whole of the entire lung, decided by the AI algorithm, and eGFR replicate the severity of COVID-19 pneumonia.
Frequency of optimistic anti-PF4/polyanion antibody checks after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2
Vaccination utilizing the adenoviral vector COVID-19 vaccine ChAdOx1 nCoV-19 (AstraZeneca) has been related to uncommon vaccine-induced immune thrombotic thrombocytopenia (VITT). Affected sufferers take a look at strongly optimistic in PF4/polyanion enzyme immunoassays (EIAs) and serum-induced platelet activation is maximal within the presence of PF4.
We decided the frequency of anti-PF4/polyanion antibodies in wholesome vaccinees and assessed whether or not PF4/polyanion EIA-positive sera exhibit platelet-activating properties after vaccination with ChAdOx1 nCoV-19 (n=138) or BNT162b2 (BioNTech/Pfizer; n=143). In whole, 19 of 281 contributors examined optimistic for anti-PF4/polyanion antibodies post-vaccination (All: 6.8% [95%CI, 4.4-10.3]; BNT162b2: 5.6% [95%CI, 2.9-10.7]; ChAdOx1 nCoV-19: 8.0% [95%CI, 4.5-13.7%]).
Optical densities have been largely low (between 0.5-1.Zero items; reference vary, <0.50) and not one of the PF4/polyanion EIA-positive samples induced platelet activation within the presence of PF4. We conclude that optimistic PF4/polyanion EIAs can happen after SARS-CoV-2 vaccination with each mRNA- and adenoviral vector-based vaccines, however the majority of those antibodies seemingly have minor (if any) medical relevance.
Accordingly, low-titer optimistic PF4/polyanion EIA outcomes needs to be interpreted with warning when screening asymptomatic people after vaccination in opposition to Covid-19. Pathogenic platelet-activating antibodies that trigger VITT don’t happen generally following vaccination.
s-xe
s-xe

Mouse anti Human Galectin-1 Antibody, Mouse MAb

MBS2543309-006mL 0.06mL
EUR 250

Mouse anti Human Galectin-1 Antibody, Mouse MAb

MBS2543309-012mL 0.12mL
EUR 370

Mouse anti Human Galectin-1 Antibody, Mouse MAb

MBS2543309-02mL 0.2mL
EUR 550

Human Galectin-1 (Gal-1) Antibody

30005-05111 150 ug
EUR 215

Human Galectin( Galectin) Elisa Kit

EK711568 96 Wells
EUR 0.18

RABBIT ANTI HUMAN GALECTIN-3:Biotin

MBS222930-005mg 0.05mg
EUR 655

RABBIT ANTI HUMAN GALECTIN-3:Biotin

MBS222930-5x005mg 5x0.05mg
EUR 2780

Rabbit Anti-Human Galectin-1

102-PA131 100ug
EUR 240

Anti-Human Galectin-1 Antibody

102-P131 100 µg
EUR 245.7
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

Anti-Human Galectin-1 Antibody

102-PA131AG 50 µg
EUR 157.5
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

Anti-Human Galectin-1 Antibody

102-PA131S 100 µg
EUR 126
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

human anti-human galectin-3 mAb(2D)

E4A09H10-2D 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(5F)

E4A09H10-5F 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(A5)

E4A09H10-A5 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(G2)

E4A09H10-G2 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(H3)

E4A09H10-H3 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(T1)

E4A09H10-T1 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Human Galectin-1 (LGALS1)

1-CSB-EP012882HU
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-1 (LGALS1)

1-CSB-EP012882HUb1
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody

MBS2543310-006mL 0.06mL
EUR 250

Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody

MBS2543310-012mL 0.12mL
EUR 370

Mouse anti Human Galectin-1/LGALS1 Monoclonal Antibody

MBS2543310-02mL 0.2mL
EUR 550

human anti-human galectin-3 mAb(N13)

E4A09H10-N13 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Human Galectin-1 Protein

PRP1033-100g 100 µg
EUR 309

Human Galectin-1 Protein

PRP1033-1mg 1 mg
EUR 1099

Human Galectin-1 Protein

PRP1033-20g 20 µg
EUR 79

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543912-006mL 0.06mL
EUR 250

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543912-012mL 0.12mL
EUR 370

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543912-02mL 0.2mL
EUR 550

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543913-006mL 0.06mL
EUR 250

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543913-012mL 0.12mL
EUR 370

Rabbit anti Human Galectin-1/LGALS1  Monoclonal Antibody

MBS2543913-02mL 0.2mL
EUR 550

Anti Human Galectin-3 Polyclonal Antibody

KH040 each
EUR 778.8
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-48T 48T Ask for price

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-96T 96T Ask for price

Recombinant Human Galectin-1

7-00427 10µg Ask for price

Recombinant Human Galectin-1

7-00428 50µg Ask for price

Recombinant Human Galectin-1

7-00429 1mg Ask for price

Recombinant Human Galectin-1

AP60482 100ug
EUR 449

Recombinant Human Galectin-1

HEOPP-0710 10ug Ask for price

RECOMBINANT HUMAN GALECTIN-1

GWB-BEA2B0 0.05 mg Ask for price

Recombinant Human Galectin-1

cyt-544-10g 10µg
EUR 60

Recombinant Human Galectin-1

cyt-544-1mg 1mg
EUR 1350

Recombinant Human Galectin-1

cyt-544-50g 50µg
EUR 145

Recombinant Human Galectin-1

MBS143303-001mg 0.01mg
EUR 240

Recombinant Human Galectin-1

MBS143303-005mg 0.05mg
EUR 310

Recombinant Human Galectin-1

MBS143303-1mg 1mg
EUR 1515

Recombinant Human Galectin-1

MBS143303-5x1mg 5x1mg
EUR 6485

RECOMBINANT HUMAN GALECTIN-1

MBS232407-005mg 0.05mg
EUR 500

RECOMBINANT HUMAN GALECTIN-1

MBS232407-5x005mg 5x0.05mg
EUR 2070

Recombinant Human Galectin-1

P1229-.01 10ug
EUR 108.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Human Galectin-1

P1229-.1 10X10ug
EUR 450.4
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Human Galectin-1

P1229-.5 50X10ug
EUR 1010.4
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Human Galectin-1

MBS9420409-002mg 0.02mg
EUR 285

Recombinant Human Galectin-1

MBS9420409-01mg 0.1mg
EUR 470

Recombinant Human Galectin-1

MBS9420409-1mg 1mg
EUR 1785

Recombinant Human Galectin-1

MBS9420409-5x1mg 5x1mg
EUR 7885

Recombinant Human Galectin-1

MBS966052-002mgEColi 0.02mg(E-Coli)
EUR 255

Recombinant Human Galectin-1

MBS966052-01mgEColi 0.1mg(E-Coli)
EUR 405

Recombinant Human Galectin-1

MBS966052-1mgEColi 1mg(E-Coli)
EUR 1425

Recombinant Human Galectin-1

MBS966052-5x1mgEColi 5x1mg(E-Coli)
EUR 6215

anti- Galectin-1 antibody

FNab03314 100µg
EUR 606.3
Description: Antibody raised against Galectin-1

anti- Galectin-1 antibody

FNab03315 100µg
EUR 658.5
Description: Antibody raised against Galectin-1

Anti- Galectin-1 Antibody

GWB-6F6392 0.1 mg Ask for price

Human Galectin 1 Protein

20-abx066725
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Galectin-1 Antibody Pair Set

ABPR-ZB244 5 plates, 15 plates Ask for price
Description: Quantitative determination of Human Galectin-1

Galectin-1, human recombinant

4648-10 each
EUR 170.4

Galectin-1, human recombinant

4648-1000 each
EUR 1977.6

Galectin-1, human recombinant

4648-50 each
EUR 314.4

Galectin-1 Human Recombinant

rAP-2252 Inquiry Ask for price

Galectin-1 (human), (recombinant)

MBS567229-01mg 0.1mg
EUR 750

Galectin-1 (human), (recombinant)

MBS567229-5x01mg 5x0.1mg
EUR 3320

Anti-Human Galectin-1 Azide Free

MBS335796-02mg 0.2mg
EUR 290

Anti-Human Galectin-1 Azide Free

MBS335796-05mg 0.5mg
EUR 555

Anti-Human Galectin-1 Azide Free

MBS335796-5x05mg 5x0.5mg
EUR 2465

Anti-Human Galectin-1 Azide Free

MBS335797-02mg 0.2mg
EUR 290

Anti-Human Galectin-1 Azide Free

MBS335797-05mg 0.5mg
EUR 555

Anti-Human Galectin-1 Azide Free

MBS335797-5x05mg 5x0.5mg
EUR 2465

Human Galectin-1 ELISA Kit

EK5323 96 tests
EUR 599

Human Galectin-1 ELISA Kit

IHULGALS1KT each
EUR 702
Description: Human Galectin-1 ELISA Kit

Human Galectin-1 ELISA Kit

MBS765403-10x96StripWells 10x96-Strip-Wells
EUR 3900

Human Galectin-1 ELISA Kit

MBS765403-48StripWells 48-Strip-Wells
EUR 340

Human Galectin-1 ELISA Kit

MBS765403-5x96StripWells 5x96-Strip-Wells
EUR 2045

Human Galectin-1 ELISA Kit

MBS765403-96StripWells 96-Strip-Wells
EUR 455

Human Galectin-1 ELISA Kit

MBS8414441-1Kit 1Kit
EUR 755

Human Galectin-1 ELISA Kit

MBS8414441-5x1Kit 5x1Kit
EUR 3455

Human Galectin-1 ELISA Kit

MBS2883188-10x96StripWells 10x96-Strip-Wells
EUR 3290

Human Galectin-1 ELISA Kit

MBS2883188-48StripWells 48-Strip-Wells
EUR 340

Human Galectin-1 ELISA Kit

MBS2883188-5x96StripWells 5x96-Strip-Wells
EUR 1800

Human Galectin-1 ELISA Kit

MBS2883188-96StripWells 96-Strip-Wells
EUR 435

Covid-19 antigen take a look ating: higher than we all know? A take a look at accuracy research

Background: Antigen testing for SARS-CoV-2 is taken into account to be much less delicate than the usual reference methodology – real-time PCR (RT-PCR). It has been steered that many sufferers with optimistic RT-PCR ‘missed’ by antigen testing could be non-infectious.
Strategies: In a real-world high-throughput setting for asymptomatic or mildly symptomatic sufferers, 494 sufferers have been examined utilizing RT-PCR in addition to a single lateral movement antigen take a look at (Ecotest, AssureTech, China). The place the outcomes differed, virus viability was evaluated by cell tradition. The take a look at parameters have been calculated with RT-PCR and RT-PCR adjusted on viability as reference requirements.
Outcomes: The general sensitivity of the used antigen take a look at associated to the RT-PCR solely was 76.2%, specificity was 97.3%. Nonetheless, 36 out of 39 sufferers ‘missed’ by the antigen take a look at contained no viable virus. After adjusting on that, the sensitivity grew to 97.7% and, extra importantly for illness management functions, the unfavorable predictive worth reached 99.2%.
Conclusions: We suggest that viability testing needs to be all the time carried out when evaluating a brand new antigen take a look at. A well-chosen and validated antigen take a look at gives glorious leads to figuring out sufferers who’re shedding viable virus (though some caveats nonetheless stay) within the real-world high-throughput setting of asymptomatic or mildly symptomatic people.

Extended Optimistic COVID-19 Check in Recovered Affected person

Coronavirus illness 2019 (COVID-19), brought on by the novel extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a world pandemic that has affected hundreds of thousands worldwide since its preliminary outbreak in Wuhan, China in December 2019. Dialogue of atypical instances of COVID-19 is crucial to gaining perception into the medical displays of this an infection.
The authors report a case wherein a 74-year-old feminine who sought medical analysis by way of telemedicine for chief complaints of recurrent low-grade fever, dyspnea, dry cough, and myalgias and subsequently examined optimistic for the SARS-CoV-2 a number of occasions in over 7 weeks regardless of prior decision of signs. The affected person’s 78-year-old husband who resides in the identical family additionally contracted the SARS-CoV-2.

Antibody (Serology) Assessments for COVID-19: a Case Research

Serology (antibody) checks to detect earlier SARS-CoV-2 an infection have been in excessive demand from the start of the COVID-19 pandemic. The preliminary scarcity of diagnostic checks coupled with asymptomatic infections led to a major demand for serology checks to establish previous infections.
Regardless of critical limitations on the interpretation of a optimistic antibody take a look at by way of immunity to SARS-CoV-2, antibody testing was initially thought-about for launch from social distancing, return to employment, and “immunity passports.”
The regulatory strategy to antibody checks was restricted; producers have been inspired to develop and market antibody checks with out submitting validation information to the FDA. FDA steering grew extra stringent, however many poor-quality checks have been already on the market-potentially inappropriately used for particular person decision-making. This can be a case research describing COVID-19 serology checks and the U.S. market and describes classes discovered for a future well being safety disaster.

Add a Comment

Your email address will not be published. Required fields are marked *